Acute disseminated encephalomyelitis after influenza vaccination
H. Saito, M. Endo, S. Takase and K. Itahara
A 12-year-old, previously healthy boy was seen with typical signs of acute
disseminated encephalomyelitis four days after influenza vaccination.
Computerized tomography demonstrated an extensive subcortical low-density
area in the left cerebral hemisphere. The CSF contained elevated levels of
immunoglobulins, especially IgG, and an abnormal kappa:lambda chain ratio.
Skin tests for hypersensitivity to egg protein were negative, but
reaugmentation of CSF protein and immunoglobulin levels was observed within
ten days after skin tests.
