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A Complication of Systemic Lupus Erythematosus

Roger E. Kelley, MD; Norman Stokes, MD; Patricio Reyes, MD; Sami I. Harik, MD

Arch Neurol. 1980;37(8):526-527.

Abstract
• A 29-year-old woman with a five-year history of systemic lupus erythematosus was seen after having had a grand mal convulsion, her first manifestation of a seizure disorder. A lumbar puncture revealed the presence of subarachnoid blood, and angiography demonstrated a fusiform aneurysm of the left posterior communicating artery. The patient's neurological status deteriorated despite the use of corticosteroids in high dosage, and she died three weeks after admission. Necropsy disclosed focal transmural angiitis at the site of the ruptured aneurysm. This report describes a radiographically and pathologically confirmed case of CNS lupus producing focal angiitis of a medium-sized cerebral vessel with secondary aneurysm formation.

Author Affiliations
From the Departments of Neurology (Drs Kelley and Harik), Radiology (Dr Stokes), and Pathology (Dr Reyes), University of Miami Medical Center.

Footnotes
Accepted for publication Dec 28, 1979.

Reprint requests to Department of Neurology, University of Miami Medical Center, PO Box 016960, Miami, FL 33101 (Dr Harik).

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