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Carol A. Tamminga, MD; Thomas N. Chase, MD

Arch Neurol. 1980;37(4):204-205.

Abstract
• Dopamine agonist therapy using se lected drugs at particular dosage levels has been found to have therapeutic benefit in certain dyskinetic syndromes. Two ergot derivatives with dopamine agonist properties were administered at relatively low doses to eight neuroleptic-free schizophrenic patients with tardive dyskinesia. Neither agent significantly improved dyskinetic symptoms; no symptoms worsened. Dopamine agonists likely vary in their selective activation of functionally distinct dopamine receptors.

Author Affiliations
From the Experimental Therapeutics Branch, National Institute of Neurological and Communicative Disorders and Stroke, National Institutes of Health, Bethesda, MD.

Footnotes
Accepted for publication April 20, 1979.

Reprint requests to Experimental Therapeutics Branch, National Institute of Neurological and Communicative Disorders and Stroke, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20205 (Dr Tamminga).

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