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Rhabdomyolysis During Treatment With Epsilon-Aminocaproic Acid
Charles W. Britt, Jr, MD;
Randall R. Light, MD;
Bruce H. Peters, MD;
Sydney S. Schochet, Jr, MD
Arch Neurol. 1980;37(3):187-188.
Abstract
• Severe rhabdomyolysis and acute renal failure occurred in a patient receiving epsilon-aminocaproic acid. The lack of evidence of vascular involvement in the muscle biopsy specimen suggests that epsilon-aminocaproic acid may have direct myotoxicity. This drug may produce a spectrum of muscle disease from mild myopathy to life-threatening rhabdomyolysis.
Author Affiliations
From the Departments of Neurology (Drs Britt, Light, and Peters) and Pathology (Dr Schochet), University of Texas Medical Branch, Galveston, Tex.
Footnotes
Accepted for publication Feb 9, 1979.
Reprint requests to Department of Neurology, University of Texas Medical Branch, Galveston, TX 77550 (Dr Peters).
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