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Joseph C. Marcus, MB, BCh, FCP(SA); John M. Pettifor, MB, BCh, FCP(SA)

Arch Neurol. 1980;37(12):772-774.

Abstract
• Ninety poorly nourished, ambulant, epileptic children, who had been receiving anticonvulsant medications for at least one year, were studied in respect to their folic acid and vitamin D metabolism. Only 11 (12.2%) had borderline or low folate levels. Serum vitamin D levels were low in five (8.9%); serum calcium levels were low in nine (10%); and serum phosphorus levels were low in three (3.3%). Alkaline phosphatase levels were elevated in 19 (21.1%), but whether these arose from bone or liver was not determined. Height retardation did not correlate with abnormal mineral metabolism.

Author Affiliations
From the Department of Pediatrics, Coronation Hospital (Dr Marcus); and the Metabolic Research Unit, Baragwanath Hospital (Dr Pettifor), Johannesburg, South Africa. Dr Marcus is now with the State University of New York Downstate Medical Center, Brooklyn.

Footnotes
Accepted for publication Feb 12, 1980.

Reprints not available.

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