Cramps, muscle pain, and tubular aggregates
R. P. Lazaro, G. M. Fenichel, A. W. Kilroy, A. Saito and S. Fleischer
A 31-year-old man had a nine-year history of exercise-induced cramps and
muscle pain without myoglobinuria. Results of laboratory investigations
differentiated his condition from the known disorders of carbohydrate and
lipid metabolism. Light and electron microscopic examination of a muscle
biopsy specimen showed tubular aggregates confined to type II fibers.
Although the relationship of tubular aggregates to muscle cramps is
uncertain, this association has been described previously and may be
significant.