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The Effect of Choline Chloride

Kenneth L. Davis, MD; Richard C. Mohs, PhD; Jared R. Tinklenberg, MD; Leo E. Hollister, MD; Adolf Pfefferbaum, MD; Bert S. Kopell, MD

Arch Neurol. 1980;37(1):49-52.

Abstract
• Young normal subjects received 16 g of choline chloride in a double-blind A-B-A design. Short- and long-term memory function was evaluated. Comparison of group means indicated that choline chloride did not significantly affect shortterm memory or long-term memory. However, individual subjects may have had some aspects of long-term memory affected by choline chloride treatments. The results suggest that the effect of lower doses of choline on long-term memory should be evaluated.

Author Affiliations
From the Stanford (Calif) University School of Medicine, and the Veterans Administration Hospital, Palo Alto, Calif (Drs Tinklenberg, Hollister, Pfefferbaum, and Kopell); the Mount Sinai School of Medicine, and the Psychiatry Service, Bronx VA Hospital, New York (Drs Davis and Mohs).

Footnotes
Accepted for publication Feb 26, 1979.

Reprint requests to Bronx Veterans Administration Hospital, Psychiatry Service (A223), 130 Kingsbridge Rd, Bronx, NY 10468 (Dr Davis).

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