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I. From Wepfer to Moniz

E. Steven Gurdjian, MD; Edwin S. Gurdjian, MD

Arch Neurol. 1979;36(6):340-343.

Abstract
• Occlusive cerebrovascular disease of carotid and vertebral arteries was described by Wepfer in 1658 and by Willis in 1665. Wepfer thought apoplexy resulted from occlusive disease of the vessels. Willis described collateral channels between these vessels, which prevented the development of stroke.

Author Affiliations
From the Department of Neurosurgery, Wayne State University School of Medicine (E. S. Gurdjian, MD) and Harper-Grace Hospitals (Edwin S. Gurdjian, MD), Detroit.

Footnotes
Accepted for publication May 1, 1978.

Reprint requests to Department of Neurosurgery, Wayne State University School of Medicine, Detroit, MI 48201 (Dr E. Steven Gurdjian).

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