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Iftekhar Ahmed, MD; Joanna Sher, MD

Arch Neurol. 1979;36(4):231-232.

Abstract
• A 42-year-old woman with a ruptured saccular aneurysm of the internal carotid artery developed large areas of cerebral leukomalacia, resulting in hemiparesis and an obtunded mental state. A significant factor in the development of the white matter lesions was episodic hypotension, leading to reduced cerebral blood flow in a patient whose cerebral circulation was already compromised by vasospasm secondary to the subarachnoid hemorrhage. This case illustrates yet another clinical situation associated with the development of white matter necrosis.

Author Affiliations
From the Department of Pathology, Downstate Medical Center, Brooklyn, NY.

Footnotes
Accepted for publication March 3, 1978.

Reprint requests to Department of Pathology, Downstate Medical Center, Brooklyn, NY 11203 (Dr Sher).

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