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Clinical and Radiologic Remission in Reticulum Cell Sarcoma of the Brain
Roger S. Williams, MD;
Robert M. Crowell, MD;
C. Miller Fisher, MD;
Kenneth Davis, MD;
Michael H. Lavyne, MD;
Allan H. Ropper, MD;
Alfonso M. Bremer, MD
Arch Neurol. 1979;36(4):206-210.
Abstract
• Two patients with cerebral reticulum cell sarcoma (CRCS) are reported in whom neurologic abnormalities and radiologic (computerized tomographic [CT] scan) evidence of tumor remitted. In one patient, remission followed craniectomy and corticosteroid therapy and lasted for eight months. In the other patient, at least four remissions occurred over a span of seven years, each in conjunction with the administration of corticosteroids. Corticosteroids may favorably alter the biologic activity of tumor tissue in some cases of CRCS, predisposing to clinical remission and disappearance of tumor on CT scan.
Author Affiliations
From the Neurological (Drs Williams, Fisher, and Ropper) and Neurosurgical (Drs Crowell and Lavyne) Services, and the Radiological Service, Department of Neuroradiology (Dr Davis), Massachusetts General Hospital, Boston, and the Department of Neurosurgery, Millard Fillmore Hospital, Buffalo, NY (Dr Bremer).
Footnotes
Accepted for publication May 11, 1978.
Reprint requests to Eunice Kennedy Shriver Center, 200 Trapelo Rd, Waltham, MA 02154 (Dr Williams).
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