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A Mesencephalic 'Locked-in Syndrome'?

Otmar Meienberg, MD; Marco Mumenthaler, MD; Kazimierz Karbowski, MD

Arch Neurol. 1979;36(11):708-710.

Abstract
• Upper lid and vertical eye movements are usually preserved in patients with the "locked-in" syndrome, a condition manifested by anarthria, spastic quadriparesis, and intact mental function, and caused by lesions in the ventral portion of the pons. We describe a presumed mesencephalic "locked-in" syndrome in a patient who had total bilateral ptosis at the onset of his disease and later on experienced complete bilateral oculomotor nerve paralysis.

Author Affiliations
From the Neurological Department, University of Berne, Switzerland.

Footnotes
Accepted for publication Nov 18, 1978.

Reprint requests to Neurological University Clinic, Inselspital, CH 3010, Berne, Switzerland (Dr Meienberg).

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