This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (19)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

A Case Report

Anthony Kales, MD; Roger Cadieux, MD; Constantin R. Soldatos, MD; Tjiauw-Ling Tan, MD

Arch Neurol. 1979;36(10):650-651.

Abstract
• A patient with severe narcolepsy and cataplexy had been treated with a high dosage of methylphenidate hydrochloride, but the drug was not effective. To relieve the patient's cardiac arrhythmia, which was assumed to be secondary to drug therapy, we withdrew methylphenidate therapy and started propranolol hydrochloride therapy. When the dosage of propranolol was increased to a level consistent with maximum β-adrenergic receptor blockade, the attacks were eliminated.

Author Affiliations
From the Department of Psychiatry and the Sleep Research and Treatment Center (Drs Kales and Soldatos), and the Department of Psychiatry (Drs Cadieux and Tan), College of Medicine, Pennsylvania State University, Hershey, Pa.

Footnotes
Accepted for publication April 15, 1979.

Reprint requests to Sleep Research and Treatment Center, The Pennsylvania State University, Milton S. Hershey Medical Center, Hershey, PA 17033 (Dr Kales).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Propranolol in Ataxia and in Aggression: Central Actions
LeFever
Arch Neurol 1986;43:9-9.
ABSTRACT  

Treatment of Narcolepsy-Reply
Kales et al.
Arch Neurol 1980;37:736-736.
ABSTRACT