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Hossein Safdari, MD; Edward P. Richardson, Jr, MD

Arch Neurol. 1979;36(10):638-642.

Abstract
• A previously healthy 20-year-old woman died of a progressive cerebral disease that involved the brain stem and the cerebral hemispheres successively. The illness ran its course in 80 days. Postmortem examination showed a multifocal necrotizing encephalopathy that chiefly affected gray matter structures and that was mainly located in the brain stem and cerebral cortex. The cause and pathogenesis remain unknown.

Author Affiliations
From the C. S. Kubik Laboratory for Neuropathology, James Homer Wright Pathology Laboratories, Massachusetts General Hospital and the Department of Neurology-Neuropathology, Harvard Medical School, Boston.

Footnotes
Accepted for publication Dec 17, 1978.

Reprint requests to Massachusetts General Hospital, Fruit St, Boston, MA 02114 (Dr Richardson).

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ABSTRACT