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  Vol. 35 No. 9, September 1978 TABLE OF CONTENTS
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The Lissencephaly (Agyria) Syndrome in Siblings

Computerized Tomographic and Neuropathologic Findings

Carlos A. Garcia, MD; David Dunn, MD; Richard Trevor, MD

Arch Neurol. 1978;35(9):608-611.


Abstract

• Two consecutive nontwin siblings had the lissencephalic syndrome. The literature of this syndrome in siblings is reviewed, and the somatic and the clinicopathologic features are delineated further. Computerized tomography is reported for the first time to our knowledge in this entity as an important, noninvasive, and possibly specific test. Diagnosis early in life is possible for adequate management of the patients and genetic counseling.



Author Affiliations

From the Charity Hospital of Louisiana; the Departments of Pathology and Neurology (Dr Garcia) and Radiology (Dr Trevor), Louisiana State University School of Medicine; and the Department of Neurology, Tulane University School of Medicine (Dr Dunn), New Orleans.


Footnotes

Accepted for publication Nov 8, 1977.

Reprint requests to Department of Neurology, Louisiana State University Medical Center, 1542 Tulane Ave, New Orleans, LA 70112 (Dr Garcia).



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