Subacute demyelinating polyneuropathy responding to corticosteroid treatment
S. J. Oh
Ten patients with subacute demyelinating neuropathy responded
satisfactorily to corticosteroid treatment. The most prominent features in
these cases were (1) subacute progression of diffuse polyneuropathy over
weeks and months, (2) high spinal fluid protein level, (3) marked nerve
conduction abnormalities, and (4) high rate of relapse. The sural nerve
biopsy specimen showed "demyelinating neuropathy." This subacute
demyelination neuropathy appears to be a distinct and clinically
identifiable entity in which corticosteroid treatment is indicated.