This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (32)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

John S. Meyer, MD; Fumihiko Sakai, MD; Hiroaki Naritomi, MD

Arch Neurol. 1978;35(6):350-359.

Abstract
• Cerebrovascular functional reserve was tested by noninvasive measurement of regional cerebral blood flow (nrCBF) at rest in quiet darkness and when repeated during standard multiple psychophysiologic activation. The test was applied to normal volunteers and patients with different neurologic disorders. The test included counting, conversation, music, and observing movements, while rCBF was measured over both cerebral hemispheres, brain stem, and cerebellum. In normal persons at rest, mean gray matter flow (Fg) values were the same for each hemisphere. Highest Fg values were observed in brain stem and both frontal regions. During activation in normal persons, there was a significant increase in Fg values over both hemispheres and in brain stem. During activation, three types of abnormal rCBF responses were seen: Demented patients showed no change, patients with vascular occlusion showed little or no increase over the ischemic hemisphere, and some patients with epilepsy showed excessive increases.

Author Affiliations
Patricia Grant

From the Baylor Center for Cerebrovascular Research and the Department of Neurology, Baylor College of Medicine, Houston.

Footnotes
Accepted for publication Oct 7, 1977.

Reprint requests to Cerebrovascular Research, Houston Veterans Administration Hospital, 2002 Holcombe Blvd, Houston, TX 77211 (Dr Meyer).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Hyperfrontal Pattern of Human Cerebral Circulation: Variations With Age and Atherosclerotic State
Mamo et al.
Arch Neurol 1983;40:626-632.
ABSTRACT  

Aging and Cerebral Vasodilator Responses to Hypercarbia: Responses in Normal Aging and in Persons With Risk Factors for Stroke
Yamamoto et al.
Arch Neurol 1980;37:489-496.
ABSTRACT  

Noninvasive Regional Cerebral Blood Flow Measurements in Dementia
Yamaguchi et al.
Arch Neurol 1980;37:410-418.
ABSTRACT  

Pathogenesis of Transient Ischemic Attacks Within the Vertebrobasilar Arterial System
Naritomi et al.
Arch Neurol 1979;36:121-128.
ABSTRACT  

Regional Cerebral Blood Flow and EEG in Patients With Epilepsy
Sakai et al.
Arch Neurol 1978;35:648-657.
ABSTRACT