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Human Botulism Studied With Single-Fiber Electromyography
Hans H. Schiller, MD;
Erik Stålberg, MD
Arch Neurol. 1978;35(6):346-349.
Abstract
• In two cases of mild human botulism, conventional electromyography (EMG) was normal. In one case, the investigation with repetitive nerve stimulation showed slightly abnormal results, but in the other case the findings were within normal limits. Single-fiber EMG showed abnormal neuromuscular function and at later investigations as well, when the patient no longer showed any muscular fatigability. The jitter was frequency dependent and decreased with higher innervation frequency. The single-fiber EMG findings normalized after three months.
The results are in agreement with the known disturbance of acetylcholine release.
Author Affiliations
From the Department of Neurology, University Hospital, Zurich, Switzerland (Dr Schiller), and the Department of Clinical Neurophysiology, University Hospital, Uppsala, Sweden (Dr Stålberg).
Footnotes
Accepted for publication Oct 26, 1977.
Reprint requests to Department of Neurology, University Hospital, CH-8091 Zurich, Switzerland (Dr Schiller).
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