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Abnormal Iris Vasculature in Myotonic DystrophyAn Anterior Segment Angiographic Study
Lawrence Z. Stern, MD;
Harold E. Cross, MD, PhD;
Alan R. Crebo, MD
Arch Neurol. 1978;35(4):224-227.
Abstract
• The microvasculature of the iris was studied in 35 patients with neuromuscular disease and 14 control subjects, using anterior segment fluorescein angiography. Myotonic muscular dystrophy, in which a variety of ocular changes have previously been reported, was found to be associated with both focal and generalized vascular abnormalities. Changes were seen in the fluorescein angiograms of all nine of the myotonic dystrophy patients in which the iris vessels could be seen. No evidence of a microcirculatory disorder was seen in patients with Duchenne's dystrophy, for which a vascular pathogenesis has been proposed. The angiograms of patients with limb-girdle dystrophy, facioscapulohumeral dystrophy, and Friedreich's ataxia were also normal.
Author Affiliations
From the Department of Neurology (Dr Stern) and the Division of Ophthalmology (Drs Cross and Crebo), the University of Arizona College of Medicine, Tucson, Ariz.
Footnotes
Accepted for publication July 7, 1977.
Reprint requests to the University of Arizona Health Sciences Center, Tucson, AZ 85724 (Dr Stern).
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