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A 53-Year Experience

Jane F. Donat, MD; Haruo Okazaki, MD; Manuel R. Gomez, MD; Thomas J. Reagan, MD; Hillier L. Baker, Jr, MD; Edward R. Laws, Jr, MD

Arch Neurol. 1978;35(11):736-740.

Abstract
• Thirty-four patients with pathologically confirmed primary pineal tumors were evaluated at the Mayo Clinic from 1923 through 1976. AH tumors were of germ cell or pineal cell origin. Most patients were adolescent boys with subacute increased intracranial pressure and Parinaud's syndrome. Hypothalamic symptoms were surprisingly infrequent. Direct surgical intervention was associated with high mortality, but has been more successful in recent years.

Author Affiliations
From the Departments of Neurology (Drs Donat, Gomez, and Reagan), Pathology and Anatomy (Drs Okazaki and Reagan), Diagnostic Radiology (Dr Baker), and Neurologic Surgery (Dr Laws), Mayo Clinic and Mayo Foundation, Rochester, Minn.

Footnotes
Accepted for publication Jan 19, 1978.

Reprint requests to Section of Publication, Mayo Clinic, 200 First St SW, Rochester, MN 55901 (Dr Donat).

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