This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (207)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Je G. Chi, MD; Elizabeth C. Dooling, MD; Floyd H. Gilles, MD

Arch Neurol. 1977;34(6):346-348.

Abstract
• Left-right asymmetries of the transverse temporal (Heschl) gyri and the temporal plane become recognizable by 31 weeks' gestation. The transverse temporal gyri are larger in number and extent on the right side in 54% of 207 serially sectioned fetal brains ranging in gestational age from 10 to 44 weeks, and the temporal plane is larger on the left side in those brains. There are two transverse temporal gyri on the left and a single right transverse temporal gyrus on the right in 18% of the brains. No asymmetry of number of transverse temporal gyri or extent of the temporal plane is apparent in 28%. These findings, which confirm those in adult brains, suggest that anatomical asymmetries for left hemispheral speech and language dominance may be established during the last trimester of fetal life.

Author Affiliations
From the Department of Pathology (Neuropathology), Children's Hospital Medical Center and the Department of Neurology (Neuropathology), Harvard Medical School, Boston.

Footnotes
Accepted for publication Feb 8, 1977.

Reprint requests to Children's Hospital Medical Center, 300 Longwood Ave, Boston, MA 02115 (Dr Gilles).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Predicting Language Lateralization from Gray Matter
Josse et al.
J. Neurosci. 2009;29:13516-13523.
ABSTRACT | FULL TEXT  

Spatial Distribution of Deep Sulcal Landmarks and Hemispherical Asymmetry on the Cortical Surface
Im et al.
Cereb Cortex 2009;0:bhp127v1-bhp127.
ABSTRACT | FULL TEXT  

Language Networks in Children: Evidence from Functional MRI Studies
Vannest et al.
Am. J. Roentgenol. 2009;192:1190-1196.
ABSTRACT | FULL TEXT  

Why are some people left-handed? An evolutionary perspective
Llaurens et al.
Phil Trans R Soc B 2009;364:881-894.
ABSTRACT | FULL TEXT  

Structural Asymmetries in the Infant Language and Sensori-Motor Networks
Dubois et al.
Cereb Cortex 2009;19:414-423.
ABSTRACT | FULL TEXT  

From the Cover: PET and MRI show differences in cerebral asymmetry and functional connectivity between homo- and heterosexual subjects
Savic and Lindstrom
Proc. Natl. Acad. Sci. USA 2008;105:9403-9408.
ABSTRACT | FULL TEXT  

Mapping the Early Cortical Folding Process in the Preterm Newborn Brain
Dubois et al.
Cereb Cortex 2008;18:1444-1454.
ABSTRACT | FULL TEXT  

Genome-wide analyses of human perisylvian cerebral cortical patterning
Abrahams et al.
Proc. Natl. Acad. Sci. USA 2007;104:17849-17854.
ABSTRACT | FULL TEXT  

Asymmetries of the planum temporale and Heschl's gyrus: relationship to language lateralization
Dorsaint-Pierre et al.
Brain 2006;129:1164-1176.
ABSTRACT | FULL TEXT  

Early Asymmetry of Gene Transcription in Embryonic Human Left and Right Cerebral Cortex
Sun et al.
Science 2005;308:1794-1798.
ABSTRACT | FULL TEXT  

The Epigenesis of Planum Temporale Asymmetry in Twins
Eckert et al.
Cereb Cortex 2002;12:749-755.
ABSTRACT | FULL TEXT  

Uncinate Fasciculus Findings in Schizophrenia: A Magnetic Resonance Diffusion Tensor Imaging Study
Kubicki et al.
Am. J. Psychiatry 2002;159:813-820.
ABSTRACT | FULL TEXT  

Asymmetry of fetal cerebral hemispheres: in utero ultrasound study
Hering-Hanit et al.
Arch. Dis. Child. Fetal Neonatal Ed. 2001;85:F194-196.
ABSTRACT | FULL TEXT  

Structural and functional brain asymmetries in human situs inversus totalis
Kennedy et al.
Neurology 1999;53:1260-1260.
ABSTRACT | FULL TEXT  

Quantifying Variability in the Planum Temporale: A Probability Map
Westbury et al.
Cereb Cortex 1999;9:392-405.
ABSTRACT | FULL TEXT  

A Magnetic Resonance Imaging Study of Planum Temporale Asymmetry in Men With Developmental Dyslexia
Rumsey et al.
Arch Neurol 1997;54:1481-1489.
ABSTRACT  

Morphologic Cerebral Asymmetries and Handedness: The Pars Triangularis and Planum Temporale
Foundas et al.
Arch Neurol 1995;52:501-508.
ABSTRACT  

In vivo evidence of structural brain asymmetry in musicians
Schlaug et al.
Science 1995;267:699-701.
ABSTRACT  

Early Surgery for Epilepsy: Redefining Candidacy
Resnick et al.
J Child Neurol 1994;9:2S36-2S41.
ABSTRACT  

Cerebral Structure on Magnetic Resonance Imaging in Language- and Learning-Impaired Children
Jernigan et al.
Arch Neurol 1991;48:539-545.
ABSTRACT  

The Morphological Substrate of Cerebral Asymmetry: the Problem of Its Measurement
Weis and Haug
Arch Neurol 1990;47:379-379.
ABSTRACT  

Learning Disabilities: A Neurobiological Perspective in Humans
Bonnet
Remedial and Special Education 1989;10:8-19.
ABSTRACT  

Dyslexia and Neurodevelopmental Pathology: Relationships to Cognition, Intelligence, and Reading Skill Acquisition
Hynd and Semrud-Clikeman
J Learn Disabil 1989;22:204-216.
ABSTRACT  

Anterior Speech Region: Asymmetry and Weight-Surface Correlation
Albanese et al.
Arch Neurol 1989;46:307-310.
ABSTRACT  

Relationships Between Laterality of Congenital Upper Limb Reduction Defects and School Performance
Dlugosz et al.
CLIN PEDIATR 1988;27:319-324.
ABSTRACT  

Computed Tomographic Scan Hemispheric Asymmetries in Right- and Left-handed Male and Female Subjects
Koff et al.
Arch Neurol 1986;43:487-491.
ABSTRACT  

Cerebral Lateralization: Biological Mechanisms, Associations, and Pathology: II. A Hypothesis and a Program for Research
Geschwind and Galaburda
Arch Neurol 1985;42:521-552.
ABSTRACT  

Cerebral Lateralization: Biological Mechanisms, Associations, and Pathology: I. A Hypothesis and a Program for Research
Geschwind and Galaburda
Arch Neurol 1985;42:428-459.
ABSTRACT  

Computed Tomographic Scan Cerebral Asymmetries and Morphologic Brain Asymmetries: Correlation in the Same Cases Post Mortem
Pieniadz and Naeser
Arch Neurol 1984;41:403-409.
ABSTRACT  

Hemispheric Asymmetries on Computed Tomographic Scans in Schizophrenia and Mania: A Controlled Study and a Critical Review
Tsai et al.
Arch Gen Psychiatry 1983;40:1286-1289.
ABSTRACT  

Cerebral Asymmetry in Developmental Dyslexia
Haslam et al.
Arch Neurol 1981;38:679-682.
ABSTRACT  

Developmental Dyslexia: Evidence for a Subgroup With a Reversal of Cerebral Asymmetry
Hier et al.
Arch Neurol 1978;35:90-92.
ABSTRACT