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Tah-Hsiung Hsu, MD

Arch Neurol. 1977;34(3):196-198.

Abstract
• Extraocular muscle pareses in patients with Cushing syndrome are virtually always associated with a greatly enlarged pituitary tumor and with advancement on oculomotor nerves. The present report concerns a patient with a rapidly progressive adrenocorticotropic hormone (ACTH)-dependent hyperadrenocorticism and sudden onset of an unilateral third nerve paresis. The patient had no demonstrable pituitary tumor. After a total adrenalectomy and correction of hyperadrenocortisolism, his third nerve paresis subsided. Ocular paresis may occur in a patient with Cushing syndrome even in the absence of mechanical involvement of ocular nerves by a pituitary tumor.

Author Affiliations
From the Division of Endocrinology and Metabolism, Department of Medicine, The Johns Hopkins Hospital, Baltimore.

Footnotes
Accepted for publication Nov 2, 1976.

Reprint requests to Blalock 909, Department of Medicine, The Johns Hopkins Hospital, Baltimore, MD 21205 (Dr Hsu).