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Bruce H. Dobkin, MD

Arch Neurol. 1977;34(3):189-190.

Abstract
• Dysesthesia and sensory and reflex loss in the legs developed in a patient treated for seizures with phenytoin (diphenylhydantoin) for one year. Her serum drug levels had been in the therapeutic range, and no other clinical toxic reactions had been noted. The peripheral neuropathy resolved when phenytoin therapy was discontinued.

Author Affiliations
From the Department of Neurology, Neuropsychiatric Institute, University of California at Los Angeles, Los Angeles.

Footnotes
Accepted for publication Oct 5, 1976.

Reprint requests to Department of Neurology, Reed Neurological Research Center, 710 West-wood Plaza, Los Angeles, CA 90024 (Dr Dobkin).