 |
|
Möbius Syndrome Due to Brain Stem Tegmental Necrosis
Nitin Thakkar, MD;
William O'Neil, MD;
John Duvally, MD;
Charlotte Liu, MD;
Mary Ambler, MD
Arch Neurol. 1977;34(2):124-126.
Abstract
• Möbius syndrome undoubtedly results from a variety of disorders affecting central or peripheral portions of appropriate cranial nerves or their target muscles. Pathological alterations observed in cranial nuclei are most often viewed as aplastic or dysplastic lesions. Two patients with Möbius syndrome with associated facial and skeletal malformations showed mineralized necrotic foci in multiple brain stem nuclei. Prenatal encephalomalacic lesions represent the pathological basis for some cases of congenital static Möbius syndrome.
Author Affiliations
From the Departments of Pathology (Drs Thakkar and Ambler) and Pediatrics (Dr O'Neil), Rhode Island Hospital, Providence, and the Departments of Pathology, Sturdy Memorial Hospital, Attleboro, Mass (Dr Duvally) and Women and Infants Hospital, Providence (Dr Liu).
Footnotes
Accepted for publication July 7, 1976.
Reprint requests to Rhode Island Hospital, 593 Eddy St, Providence, RI 02902 (Dr Ambler).
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Mobius Syndrome: Evidence for a Vascular Etiology
D'Cruz et al.
J Child Neurol 1993;8:260-265.
ABSTRACT
Evaluation and Treatment of Congenital Facial Paralysis
Harris et al.
Arch Otolaryngol Head Neck Surg 1983;109:145-151.
ABSTRACT
A Review of Congenital Neurologic Malformations
Icenogle and Kaplan
CLIN PEDIATR 1981;20:565-576.
ABSTRACT
|
