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Simmons Lessell, MD; N. Paul Rosman, MD

Arch Neurol. 1977;34(12):759-765.

Abstract
• Nine patients with the syndrome of juvenile diabetes mellitus and optic atrophy exemplified the wide range of manifestations of this syndrome. The disease may occur as a recessively inherited or sporadic disorder and tends to have multisystem involvement. Hearing loss, diabetes insipidus, and evidence of cerebellar or central vestibulo-ocular dysfunction are common.

Author Affiliations
From the Departments of Ophthalmology (Dr Lessell), Neurology (Drs Rosman and Lessell), Pediatrics (Dr Rosman), and Anatomy (Dr Lessell), Boston University School of Medicine and Boston City Hospital, Boston.

Footnotes
Accepted for publication May 31, 1977.

Reprint requests to 720 Harrison Ave, Boston, MA 02118 (Dr Lessell).

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