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Shin Joong Oh, MD; Joseph Myungho Kim, MD

Arch Neurol. 1976;33(8):583-586.

Abstract
• A young man with a long history of "huffing" of lacquer thinner developed toxic peripheral neuropathy. Clinical improvement occurred several weeks after cessation of exposure. Substantial slowing in nerve conduction was noted. Sural nerve biopsy specimen showed (1) giant axonal swelling, (2) axonal degeneration, and (3) an increased paranodal gap. We believe that "huffer's" neuropathy is a primary axonal neuropathy with secondary demyelination.

Author Affiliations
From the departments of neurology (Dr Oh) and pathology (Dr Kim), University of Alabama School of Medicine, and the Veterans Administration Hospital, Birmingham.

Footnotes
Accepted for publication April 5, 1976.

Reprint requests to Department of Neurology, University of Alabama in Birmingham, University Station, Birmingham, AL 35294 (Dr Oh).