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Myoclonus in Familial Restless Legs Syndrome
Dan Boghen, MD, FRCP(C);
Jean-Marie Peyronnard, MD, FRCP(C)
Arch Neurol. 1976;33(5):368-370.
Abstract
• Eighteen members of a family were affected over a span of five generations with the restless legs syndrome, transmitted as an autosomal dominant trait.
Ten patients had myoclonus. The propositus, a 57-year-old man, suffered from repeated, intense, asymmetric flexion jerks of the lower extremities, alternating with fidgeting and friction movements of the legs; all occurred at night prior to sleep and severely interfering with it. The patient's movements ceased with the onset of stage 1 sleep, while in his brother, the motor activity persisted in stages 1 and 2 of sleep.
Author Affiliations
From the Neurology Section, Department of Medicine, Hôtel-Dieu Hospital, and the University of Montreal.
Footnotes
Accepted for publication Sept 1, 1975.
Read in part before the 27th annual meeting of the American Academy of Neurology, Miami, 1975.
Reprint requests to Hôtel-Dieu Hospital, 3840 St Urbain St, Montreal, Quebec, Canada H2W 1T8 (Dr Boghen).
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Autosomal dominant restless legs syndrome maps on chromosome 14q
Bonati et al.
Brain 2003;126:1485-1492.
ABSTRACT
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