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Shy-Drager Syndrome With Abnormal Respirations and Antidiuretic Hormone Release
Alan H. Lockwood, MD
Arch Neurol. 1976;33(4):292-295.
Abstract
A patient with Shy-Drager syndrome exhibited a partial defect in antidiuretic hormone (ADH) release, and cluster breathing, an indication of pontomedullary respiratory center damage, with a normal CO2 response curve. This extends the spectrum of abnormalities associated with this degenerative disease of the central nervous system. The presence of a pontomedullary respiratory pattern without an impaired CO2 response curve suggests that neurons that determine respiratory rhythm function independently from those that function as chemoreceptors.
Author Affiliations
From the Department of Neurology, University of California, San Francisco.
Footnotes
Accepted for publication July 3, 1975.
Reprint requests to Department of Neurology, New York Hospital-Cornell Medical Center, 525 E 68th St, New York, NY 10021 (Dr Lockwood).
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