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Salvatore DiMauro, MD; Lewis P. Rowland, MD

Arch Neurol. 1976;33(3):204-205.

Abstract
• The urinary excretion of carnitine by boys with Duchenne dystrophy did not differ significantly from age-matched controls. Since serum and muscle concentrations of carnitine are also normal in Duchenne dystrophy, it cannot be proved that this small molecule leaks from muscle in Duchenne dystrophy. If the muscle surface membrane is abnormally leaky in Duchenne dystrophy, different molecules seem to be affected in different ways.

Author Affiliations
From the H. Houston Merritt Clinical Research Center for Muscular Dystrophy and Related Diseases, Columbia University College of Physicians and Surgeons, New York (Dr DiMauro), and the Neurological Institute of Presbyterian Hospital, New York (Dr Rowland).

Footnotes
Accepted for publication Oct 30, 1975.

Reprint requests to Department of Neurology, Columbia University College of Physicians and Surgeons, 710 W 168th St, New York, NY 10032 (Dr DiMauro).

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