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  Vol. 33 No. 11, November 1976 TABLE OF CONTENTS
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Medullary Actions of Tetanus Toxin

An Electrophysiological Study in Man

Marc Bratzlavsky, MD; Henri vander Eecken, MD

Arch Neurol. 1976;33(11):783-785.


Abstract

• Brain-stem reflexes have been studied in four patients with generalized tetanus. Inhibitory cutaneous reflexes were abolished or severely depressed. The same held true, to a lesser degree, for excitatory cutaneous reflexes with long polysynaptic pathways. Proprioceptive reflexes behaved variably. The observations are discussed in regard to the possible sources of enhanced motoneuronal activity in tetanus. It is concluded that, besides depression of inhibitory synapses on motoneurons, interneuronal damage may contribute to the tetanus symptomatology.



Author Affiliations

From the Department of Neurology, University of Ghent (Belgium).


Footnotes

Accepted for publication April 26, 1976.

Reprint requests to Department of Neurology, Academisch Ziekenhuis, De Pintelaan 135, B-9000 Gent, Belgium (Dr Bratzlavsky).



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