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Enzyme Histochemistry and Autoradiography

Willem A. den Hartog Jager, MD; A.E.F. Hugo Meijer, PhD; J.M.B. Vianney de Jong, MD

Arch Neurol. 1975;32(4):247-249.

Abstract
A comparative enzyme-histochemical study was made of the sarcoplasmic masses in a muscle biopsy specimen from a patient with myotonic dystrophy and those in the jaw-muscle of the Rana temporaria tadpole. The enzyme-histochemical patterns of the two models proved to be identical.

An autoradiographic study was made of the sarcoplasmic masses in the R temporaria tadpole with DL-thyroxine-2-¹⁴C and levomethionine ³⁵S. The radioactively labeled compounds were found to be stored or incorporated mainly in the myofibrillae, and virtually not at all in the sarcoplasmic masses.

Author Affiliations
From the laboratories of experimental neurology and pathological anatomy, Histochemical Section, Wilhelmina Gasthuis, Amsterdam.

Footnotes
Accepted for publication June 18, 1974.

Reprint requests to Department of Neurology, Wilhelmina Gasthuis, Eerste Helmersstraat 104, Amsterdam, Netherlands (Dr. Jager).