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Prednisolone Test for Muscle Diseases

Keiichi Takahashi, MD; Munetada Oimomi, MD; Takeshi Shinko, MD; Keiichi Shutta, MD; Bonpei Matsuo, MD; Tsuneo Takai, MD; Hiroo Imura, MD

Arch Neurol. 1975;32(2):89-91.

Abstract
Serum creatine phosphokinase activity increased significantly four or six hours after the administration of prednisolone in patients with muscular dystrophy of various types, whereas it did not increase in other muscular disorders. The extent of the response correlated inversely with the grade of disability. The prednisolone test may help to differentiate muscular dystrophy from polymyositis.

Author Affiliations
From the Third Department (Drs. Takahashi, Takai, and Imura) and the Second Department (Drs. Oimomi and Shinko) of Internal Medicine, Kobe University School of Medicine, Kobe, and Hyogo Chuo Hospital (Drs. Shutta and Matsuo), Sanda City, Hyogo Pref., Japan.

Footnotes
Accepted for publication June 18, 1974.

Reprint requests to Kobe University School of Medicine, Ikuta-ku, Kobe, Japan (Dr. Takahashi).

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