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Ultrastructure of Aneurysms
William E. Stehbens, MD, D Phil
Arch Neurol. 1975;32(12):798-807.
Abstract
• The fine structure of five cerebral aneurysms, four early aneurysmal changes, and three arteriovenous aneurysms (two cerebral and one spinal) was investigated from surgical and autopsy specimens. Each lesion was characterized by thickening, lamination, redundancy, and separation of basement membranes, abundant cellular debris, and a paucity or absence of elastica. In several instances, extracellular lipid and lipophages were present. These vascular lesions were remarkably similar to one another and also to the degenerative changes in experimental arteriovenous aneurysms, thus substantiating the concept that they, too, are essentially degenerative in nature.
Author Affiliations
From the departments of pathology, Albany Medical College of Union University and the Veterans Administration Hospital, Albany, NY. Dr Stehbens is now with the Wellington Clinical School and the Wellington Cancer and Medical Research Institute, Wellington, New Zealand.
Footnotes
Accepted for publication Dec 10, 1974.
Reprint requests to Department of Pathology, Wellington Clinical School, Wellington 2, New Zealand (Dr Stehbens).
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