This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Masao Kinoshita, MD; Eijiro Satoyoshi, MD

Arch Neurol. 1974;31(6):423-425.

Abstract
A 23-year-old man had muscular weakness and wasting starting in childhood. Biopsy material from quadriceps femoris showed groups of small fibers, with a selective decrease in diameter of type I fibers. Two additional biopsy specimens from deltoid showed numerous nemaline bodies in small type I fibers. Electron microscopically, two mutually perpendicular sets of striations were visualized in both cross and longitudinal sections of these bodies. These bodies seemed to consist of crystals whose sides measured 105 Angstroms and length, 180 or 370 A. The term "nemaline myopathy" was avoided because it is uncertain whether the disorder was actually myopathic.

Author Affiliations
From the Department of Internal Medicine, Toho University, Tokyo.

Footnotes
Accepted for publication June 24, 1974.

Reprint requests to Department of Internal Medicine, Toho University, Tokyo (Dr. Kinoshita).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?