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Irwin A. Brody, MD

Arch Neurol. 1974;31(5):317-319.

Abstract
Denervation of the rat hind limb was found to increase the K⁺-independent p-nitrophenylphosphatase (basic pNPPase) activity of the isolated sarcolemma. There was no change in K⁺-stimulated p-NPPase and Na⁺, K⁺-stimulated adenosine triphosphatase. This increased enzyme activity might underlie the postspike increase in K⁺ conductance of denervated sarcolemma in view of the proposal that basic p-NPPase activity is related to the rate of passive flux of K⁺.

Author Affiliations
From the Division of Neurology, Duke University Medical Center, Durham, NC.

Footnotes
Accepted for publication April 4, 1974.

Reprint requests to Division of Neurology, Duke University Medical Center, Durham, NC 27710 (Dr. Brody).

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