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  Vol. 30 No. 2, February 1974 TABLE OF CONTENTS
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Midbrain Ptosis

A Case With Clinicopathologic Correlation

John H. Growdon, MD; Gerald F. Winkler, MD; Shirley H. Wray, MD, PhD

Arch Neurol. 1974;30(2):179-181.


Abstract

A woman had bilateral ptosis and rightsided ophthalmoplegia as prominent signs of a midbrain infarct. The lesion involved the third and fourth cranial nerve nuclei on the right. The lesion extended to the left side only at the caudal extent of the infarct, in the dorsal tegmentum of the mesencephalon. This midline lesion may be responsible for the bilateral ptosis, since this finding is consistent with current models of oculomotor organization in monkeys. To our knowledge, this is the first time such correlation has been demonstrated in man.



Author Affiliations

From the Department of Neurology, Massachusetts General Hospital (Drs. Growdon, Winkler, and Wray), and the Howe Laboratory of Ophthalmology, Massachusetts Eye and Ear Infirmary (Dr. Wray), Boston.


Footnotes

Accepted for publication Aug 9, 1973.

Reprint requests to Department of Neurology, Massachusetts General Hospital, Boston 02114 (Dr. Growdon).



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Unilateral Oculomotor Palsy and Bilateral Ptosis From Paramedian Midbrain Infarction
Liu et al.
Arch Neurol 1991;48:983-986.
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Oculomotor Nuclear Complex Infarction: Clinical and Radiological Correlation
Biller et al.
Arch Neurol 1984;41:985-987.
ABSTRACT  

Levator-Sparing Oculomotor Nerve Palsy Caused by a Solitary Midbrain Metastasis
Keane et al.
Arch Neurol 1984;41:210-212.
ABSTRACT  

Quadriparesis and Nuclear Oculomotor Palsy With Total Bilateral Ptosis Mimicking Coma: A Mesencephalic 'Locked-in Syndrome'?
Meienberg et al.
Arch Neurol 1979;36:708-710.
ABSTRACT  

Neuro-ophthalmology
Lessell
Arch Ophthalmol 1975;93:434-464.
 





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