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Increased Activity of the Spinal Fluid in Psychotic Patients

Salvador Vale, MD; M. Angeles Espejel, MD; Fernando Calcaneo, MD; Judith Ocampo, QBP; Jorge Diaz-de-Leon, MD

Arch Neurol. 1974;30(1):103-104.

Abstract
Spinal fluid samples from psychotic patients were examined for creatine phosphokinase (CPK). Increased enzyme activity was found in 12 out of 40 patients. Creatine phosphokinase values ranged from 1 to 11 international units (IU)/100 ml; mean, 4 IU ± 3.5 SD.

Patients showing increased CPK values in spinal fluid were those in whom the psychotic state was in the acute phase of evolution. No other clinical correlation could be determined.

Author Affiliations
Mexico City

From the Universidad Nacional Autónoma de México, Mexico City. Dr. Vale is now at Clinica Londres, Durango 33, DF, Mexico; Dr. Espejel is now at Hospital Psiquiátrico "Fray Bernardino Alvarez," SSA, Tlalpan 22, DF, Mexico; and Drs. Calcaneo, Ocampo, and Diaz-de-Leon are with Laboratorios Clínicos de Mexico, Durango 50, DF, Mexico.

Footnotes
Accepted for publication May 31, 1973.

Reprint requests to Rosa de Castilla 9, Mexico 19, DF, Mexico (Dr. Vale).

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