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Anisocoria in Heroin Withdrawal
CPT Thomas M. Cosgriff, MC
Arch Neurol. 1973;29(3):200-201.
Abstract
Anisocoria was frequently observed during the withdrawal period in soldiers treated for heroin abuse in Vietnam. In 100 of these soldiers, the incidence of anisocoria was determined and compared with the incidence in 100 soldiers of similar age who showed no evidence of heroin use. There was a greater incidence of anisocoria among the soldiers hospitalized for heroin abuse than among the controls (P<.001). The anisocoria was transient and static, occurring during a time when one would expect to see signs and symptoms of withdrawal, and in most instances (78%) was accompanied by such signs and symptoms. Withdrawal might have operated to unmask asymmetry of visual and neural axes, thereby accounting for the anisocoria.
Author Affiliations
USA, Long Binh, Vietnam
From the US Army Drug Treatment Center, Long Binh, Vietnam.
Footnotes
Accepted for publication May 9, 1973.
Reprint requests to Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234 (Dr. Cosgriff).
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