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Acquired Syndrome in Children

Generoso Gascon, MD; David Victor, MD; Cesare T. Lombroso, MD, PhD

Arch Neurol. 1973;28(3):156-162.

Abstract
A progressive loss of comprehension and production of language occurred in three patients over a period of weeks to months, then plateaued into a stable, prolonged aphasia. The language disorder was associated with seizures which either preceded or shortly followed the onset of language loss. The seizures responded easily to anticonvulsants. Recovery from aphasia was incomplete, but comprehension of written language preceded comprehension of oral language. It is postulated that the pathophysiologic process involves bilateral temporal lobes, and that the origin is either a slowly evolving focal encephalitis or is related, in some unknown way, to convulsive disorder.

Author Affiliations
From the Seizure Unit, Department of Neurology, Children's Hospital Medical Center, Boston (Drs. Gascon, Victor, and Lombroso), and Aphasia Research Center, Boston Veterans Administration Hospital (Dr. Goodglass).

Footnotes
Accepted for publication Oct 10, 1972.

Read in part before the annual meeting of the American Epilepsy Society, New York, Dec 2, 1971.

Reprint requests to the Seizure Unit, Department of Neurology, Children's Hospital Medical Center, 300 Longwood Ave, Boston (Dr. Gascon).

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