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Protein and Enzyme Alterations in Experimental Brain Injury
Ramon Lim, MD, PhD;
Jack C. de la Torre, PhD;
Sean Mullan, MD
Arch Neurol. 1972;27(4):314-321.
Abstract
Increased intracranial pressure was produced in the cat by epidural balloon compression. An increase in the activity of sodium-potassium-adenosine triphosphatase was detected in compressed brain compared to the control brain. Alterations in the acetylcholinesterase isozymes were detected with polyacrylamide electrophoresis. Evidence obtained by immunological means suggests the release of synaptic membrane antigens following cerebral injury.
Author Affiliations
Chicago
From the Division of Neurological Surgery and the Department of Biochemistry, Pritzker School of Medicine, University of Chicago.
Footnotes
Accepted for publication April 26, 1972.
Reprint requests to Division of Neurological Surgery, University of Chicago Hospitals, 950 E 59th St, Chicago 60637 (Dr. Lim).
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