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  Vol. 27 No. 2, August 1972 TABLE OF CONTENTS
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Cytarabine Treatment of Herpes Simplex Encephalitis

William A. Farris, MD; Michael E. Blaw, MD

Arch Neurol. 1972;27(2):99-102.


Abstract

A patient with herpes simplex encephalitis whose infection was documented by both viral cultures from biopsy material and later with a rise in complement fixation titers was treated with cytarabine (cytosine arabinoside). Marked clinical improvement was temporarily related to the therapy. Cytarabine has certain advantages over the more generally used idoxuridine. These include the practical consideration of the availability of cytarabine, its ease of administration, and lesser toxicity.



Author Affiliations

Dallas

From the departments of neurology and pediatrics, the University of Texas Southwestern Medical School at Dallas. Dr. Farris is now with the Communicable Disease Center, Atlanta.


Footnotes

Accepted for publication March 21, 1972.

Reprint requests to Children's Medical Center, 1935 Amelia St, Dallas 75235 (Dr. Blaw).



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