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The Heralding and/or Major Manifestation

Allen Silverstein, MD; Gerald Steinberg, MD; Morton Nathanson, MD

Arch Neurol. 1972;26(4):353-358.

Abstract
Fifteen patients with infectious mononucleosis (IM) had neurological signs and symptoms as the major and/or heralding features of the illness. In six, the only detectable clinical manifestations were neurological. The incidence of objective neurological involvement among 144 patients hospitalized with IM was 5.5%. Infectious mononucleosis should be one of the etiological considerations in children and young adults presenting with short histories and showing neurological deficits reflecting involvement of almost any part of the nervous system. Pharyngitis, adenopathy, splenomegaly, etc, need not be present.

Author Affiliations
New York

From the Department of Neurology, Mt. Sinai School of Medicine, City University, New York, and the Department of Neurology, Long Island Jewish Medical Center, New Hyde Park, NY. Dr. Steinberg is now with the Department of Neurology, University of Miami (Fla) School of Medicine.

Footnotes
Accepted for publication Nov 24, 1971.

Read before the 96th annual meeting of the American Neurological Association, Washington, DC, June 14, 1971.

Reprint requests to the Department of Neurology, Mt. Sinai School of Medicine, City University, New York 10029 (Dr. Silverstein).

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