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Forbes H. Norris, Jr., MD; Mary Jane Aguilar, MD; Charles E. Harman, MD

Arch Neurol. 1972;26(3):212-217.

Abstract
A patient with probable systemic lupus erythematosus (SLE) was found at necropsy to have a benign brain tumor classified as an atypical vascular hamartoma. Electron microscopic study revealed myxovirus-like particles in the tumor nuclei. It is concluded that the SLE and its corticosteroid treatment caused an immunologic deficit which facilitated virus invasion of a preexisting hamartoma. This case exemplifies the possibility in a wide range of diseases that the detection of a virus may merely indicate secondary invasion of previously damaged tissue.

Author Affiliations
San Francisco

From the School of Medical Sciences, University of the Pacific, and the Institute of Medical Sciences, Pacific Medical Center, San Francisco.

Footnotes
Accepted for publication Aug 17, 1971.

Read in part before the Federation of Western Societies of Neurological Science, San Francisco, Feb 26, 1971.

Reprint requests to R513, Research Bldg, Pacific Medical Center, PO Box 7999, San Francisco 94120 (Dr. Norris).

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