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Early Manifestations of Tuberous Sclerosis

Jeffrey C. Roth, MD; Charles J. Epstein, MD

Arch Neurol. 1971;25(6):547-551.

Abstract
Tuberous sclerosis may present in the newborn period as a seizure disorder characterized as infantile spasms. An important diagnostic sign is the presence of multiple hypopigmented macules which may precede, by several years, the development of other manifestations of the disease.

Author Affiliations
San Francisco

From the Department of Pediatrics, University of California, San Francisco.

Footnotes
Accepted for publication April 27, 1971.

Reprint requests to Department of Pediatrics, University of California, Third and Parnassus, San Francisco 94122 (Dr. Epstein).

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Tuberous Sclerosis Complex in Children
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Arch Pediatr Adolesc Med 1981;135:912-917.
ABSTRACT