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Neuronal Cytoplasmic Globules in the Brain in Morquio's Syndrome
Floyd H. Gilles, MD;
Ruthmary K. Deuel, MD
Arch Neurol. 1971;25(5):393-403.
Abstract
Cytoplasmic globules limited largely to neurons in thalamus and sectors CA2, CA3, and the hilus of the fascia dentata have been found in a radiologically documented case of Morquio's Syndrome. The material within neurons is composed of at least two ultrastructurally and histochemically distinct substances: possibly a lipofuscin and a hexose-containing lipid.
Author Affiliations
Boston
From the Department of Pathology (Neuropathology) and Neurology, Children's Hospital Medical Center, and the Department of Neurology, Harvard Medical School, Boston.
Footnotes
Accepted for publication April 13, 1971.
Reprint requests to Children's Medical Center, 300 Longwood Ave, Boston 02115 (Dr. Gilles).
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