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Muscular HypertonicityEpisodes in Scottish Terrier Dogs
Kenneth M. Meyers, PhD;
William M. Dickson, DVM, PhD;
John E. Lund, DVM, PhD;
George A. Padgett, DVM
Arch Neurol. 1971;25(1):61-68.
Abstract
"Scottie cramp" is a genetic disease in Scottish terrier dogs characterized by episodes of progressive muscular hypertonicity with associated postural and locomotive difficulties. The episodes are observed during exercise. Results of clinical laboratory tests and gross and histopathological examinations were normal. Telemetered electromyograms (EMG) revealed that the interference pattern from the muscles was of longer duration and higher amplitude during the episode when compared to the preepisode recording. A normal response from the muscle was observed following tubocurarine chloride administration, epidural anesthesia, or electrical stimulation below a procaine nerve block. These data suggest the disease is of central nervous system origin. During an episode when the dog was suspended in a sling, the EMG activity was not continuous. Dorsal root section, lumbar 3, 4, and 5, did not appear to alter the EMG activity during an episode.
Author Affiliations
Pullman, Wash
From the departments of physiology and pharmacology (Drs. Meyers and Dickson) and pathology (Dr. Padgett), College of Veterinary Medicine, Washington State University, Pullman, Wash. Dr. Lund is now with the College of Veterinary Science and Medicine, Purdue University, Lafayette, Ind.
Footnotes
Accepted for publication Dec 29, 1970.
Reprint requests to Department of Physiology and Pharmacology, College of Veterinary Medicine, Washington State University, Pullman, Wash 99163 (Dr. Meyers).
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